The use of noninvasive ECG imaging for examination of a patient with Brugada syndrome

Introduction Brugada syndrome (BrS) is an inherited cardiac arrhythmia syndrome associated with electrocardiography (ECG) patterns characterized by incomplete right bundle branch block and ST segment elevation in the anterior precordial leads, correlated to an increased risk of sudden cardiac death. Genetic substrate, ECG manifestation, and risk of arrhythmia in patients with BrS vary considerably. A new strategy for the treatment of BrS patients with recurrent episodes of ventricular tachycardia (VT) or ventricular fibrillation (VF) is based on the catheter ablation of the arrhythmogenic substrate in the right ventricular outflow tract (RVOT), identified by invasive cardiac mapping. A promising alternative to catheter-based cardiac mapping is a noninvasive electrocardiographic imaging (ECGI). The current case study demonstrates the use of ECGI for diagnosis of a patient with BrS.